A rapid high yield synthesis of no-carrier-added (-)-[123I]iodocyanopindolol

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A rapid high yield synthesis of no-carrier-added (-)-[123I]iodocyanopindolol.

A convenient and efficient radiosynthesis of no-carrier-added [123I]labeled (-)iodocyanopindolol, (-)-[123I]ICYP, a high affinity beta adrenergic antagonist, is described. (-)-[123I]ICYP was synthesized by a modified chloramine-T radioiodination of (-)cyanopindolol followed by a novel reversed-phase HPLC purification that provided the radiopharmaceutical as a directly injectable solution. The t...

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ژورنال

عنوان ژورنال: International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes

سال: 1991

ISSN: 0883-2889

DOI: 10.1016/0883-2889(91)90094-h